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Product Description
LMAN1 monoclonal Antibody | MB63830 | Bioworld
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat
Application: FC, IHC, WB
Application Range: WB 1:500~2000, IHC 1:150, FLOW 1:100
Background: The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: lectin, mannose binding 1
Molecular Weight: 54.2 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60
Immunogen: Full length human recombinant protein of human LMAN1 (NP_005561) produced in Hek293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A
