Product Description
LRRFIP1 monoclonal Antibody | MB0034 | Bioworld
Host: Mouse IgG1
Reactivity: Human,Mouse
Application: WB
Application Range: WB: 1:1000
Background: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins
Molecular Weight: Predicted band size:89KDa Observed band size:160KDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GC-binding factor 2; TAR RNA-interacting protein; GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
Immunogen: Recombinant full length Human LRRFIP1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Notch Signaling,Nuclear Receptor Signaling,Cell Cycle Control G1 S Checkpoint,Epigenetic Writers and Erasers of Histone H3,Epigenetic Writers and Erasers of Histones H2A H2B and H4,