Product Description
NeuN Rabbit monoclonal Antibody | BS9837M | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB ICC/IF IHC FC
Application Range: WB: 1:1000-1:2000 ICC/IF: 1:50-1:200 IHC: 1:200-1:500 FC: 1:50-1:100
Background: Neuronal nuclei (NeuN, Fox-3, RBFOX3) is a nuclear protein expressed in most post-mitotic neurons of the central and peripheral nervous systems. NeuN is not detected in Purkinje cells, sympathetic ganglion cells, Cajal-Retzius cells, INL retinal cells, inferior olivary, and dentate nucleus neurons. This neuronal protein was originally identified by immunoreactivity with a monoclonal Antibody also called NeuN. Using MS-analysis, NeuN was later identified as the Fox-3 gene product. Fox-3 contains an RNA recognition motif and functions as a splicing regulator. Fox-3 regulates alternative splicing of NumB, promoting neuronal differentiation during development.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of NeuN and does not cross-react with related proteins.
Molecular Weight: Predicted band size:34KDa Observed band size:46, 48KDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: RNA binding protein fox-1 homolog 3; Fox-1 homolog C; RBFOX3; NeuN; Fox-3; Fox3; Neuronal Marker
Immunogen: Recombinant Antibody.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein A affinity purified
Pathway: