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Product Description
p38 Mouse monoclonal Antibody | MB9023 | Bioworld
Host: Mouse
Reactivity: Human, mouse
Application: WB ICC IHC
Application Range: WB: 1:5000 ICC: 1:100-1:200 IHC: 1:100-1:200
Background: MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38α, p38β and p38γ are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of p38 and does not cross-react with related proteins.
Molecular Weight: ~ 42 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; SAPK2a; MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A
Immunogen: This Antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to a region of p38.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein G affinity purified
Pathway: Tumor-Infiltrating Immune Cell Marker Guide,B cell receptor signaling,
