Product Description
PIM1 Rabbit monoclonal Antibody | BS9950M | Bioworld
Host: Rabbit
Reactivity: Human, Mouse
Application: WB ICC/IF IHC
Application Range: WB: 1:1000-1:2000 ICC/IF: 1:50-1:200 IHC: 1:50-1:200
Background: Pim-1 is a serine/threonine kinase that cooperates with c-Myc in lymphoid cell transformation. The expression of pim-1 increases during the progression from early to late G1, remaining high at the G1/S boundary and G2 phases of the cell cycle. Pim-1 is regulated at both the transcriptional and translational level, and it has been shown to be induced by IL-2 stimulation. Pim-1 also plays a role in T cell differentiation, and it has been shown to stimulate c-Myc-mediated apoptosis upstream of caspase-3-like proteases.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of PIM1 and does not cross-react with related proteins.
Molecular Weight: ~ 45 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Serine/threonine-protein kinase pim-1; Pim1; Pim-1
Immunogen: Recombinant Antibody.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein A affinity purified
Pathway: