Product Description
TNPO3 polyclonal Antibody | BS91365 | Bioworld
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC IF IHC
Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200
Background: The Importin complex consists of Importin-α and Importin-β proteins which assist in transport of arginine- or serine-rich (SR) proteins across the nucleus. Importin-12, also known as Transportin-3 or Transportin-SR, is a member of the Importin-β family and functions as a nuclear transport receptor for serine/arginine-rich proteins. Through recognition of phosphorylated RS domains, Importin-12 mediates the nuclear import of several SR proteins, such as splicing factors SFRS1 and SFRS2. By regulating the nucleocytoplasmic transport of these and other SR mRNA splicing factors, Importin-12 controls their access to mRNA and, therefore, acts a transcriptional regulator.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: TNPO3 polyclonal Antibody detects endogenous levels of TNPO3 protein.
Molecular Weight: 104 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Imp12, TRN-SR, TNPO3, IPO12, TNPO 3, Imp12, Importin 12, Importin-12, IPO12, MTR10A, TNPO3, TNPO3, Transportin 3, Transportin SR, Transportin-3, Transportin-SR, TRN SR, TRN-SR, TRN-SR2, TRNSR,
Immunogen: N/A
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: