Product Description
MANF polyclonal Antibody | BS8641 | Bioworld
Host: Rabbit
Reactivity: Human
Application: WB IF
Application Range: WB: 1:500~1:2000 IF: 1:50~1:200
Background: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MANF polyclonal Antibody detects endogenous levels of MANF protein.
Molecular Weight: ~ 16kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET; MANF; ARMET, ARP
Immunogen: Recombinant full length Human MANF.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: