Euro
USD
British Pound
NULL
Product Description
Dynactin 2 polyclonal Antibody | BS6937 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:2000
Background: Dynactin 2, also known as DCTN2, Dynamitin or DCTN50, is a peripheral membrane protein that is one of many subunits in the Dynactin complex. Like other Dynactin subunits, Dynactin 2 mediates Dynein-organelle binding and helps to regulate chromosome alignment during prometaphase and spindle organization during mitosis. Overexpression of Dynactin 2 disrupts the Dynactin-Dynein complex, thus inhibiting retrograde axonal transport and causing motor neuron degeneration.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Dynactin 2 polyclonal Antibody detects endogenous levels of Dynactin 2 protein.
Molecular Weight: ~ 44 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Dynactin subunit 2; 50 kDa dynein-associated polypeptide; Dynactin complex 50 kDa subunit; DCTN-50; p50 dynamitin; DCTN2; DCTN50
Immunogen: Recombinant full length Human Dynactin 2 / DCTN2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Toll-like Receptor signaling,Toll-like Receptor signaling,
