Product Description
GDI1 polyclonal Antibody | BS5731 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking. Rab GDP dissociation inhibitor (Rab GDI or GDI3) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP. In mammals, there exist two major isoforms, Rab GDI α (also known as XAP-4) and Rab GDI β. While the mammalian Rab GDI β-genes are ubiquitously expressed, the Rab GDI α genes are predominantly brain-specific. Since it is expressed predominantly in neural and sensory tissues, Rab GDI α may serve a specific function in neural signalmtransmission. The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GDI1 polyclonal Antibody detects endogenous levels of GDI1 protein.
Molecular Weight: ~ 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Rab GDP dissociation inhibitor alpha; Rab GDI alpha; Rab GDI α; Rab GDIα; RabGDIα; Guanosine diphosphate dissociation inhibitor 1; GDI-1; Oligophrenin-2; Protein XAP-4; GDIL; OPHN2; RABGDIA; XAP4
Immunogen: Synthetic peptide, corresponding to amino acids 402-447 of Human GDI1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: