Product Description
NVL polyclonal Antibody | BS5832 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Valosin containing protein (VCP), also designated TERA (for transitional endoplasmic reticulum ATPase), is a member of the AAA family of ATPases, which are involved in a variety of cellular activities. VCP is involved in a variety of membrane functions and in the regulation of the cell cycle. VCP associates with ubiquitinated IkB-a as well as with the 26S proteosome, indicating a potential role for VCP in the proteosome-mediated degradation of IkB-a. NVL (nuclear valosin-containing protein-like), also known as NVLp, is an 856 amino acid nuclear protein belonging to the AAA ATPase family. Implicated in ATP-dependent nuclear processes and ribosome synthesis, NVL exists as three alternatively spliced isoforms designated NVL isoform 1 (NVLp.2), NVL isoform 2 (NVLp.1) and NVL isoform 3. Widely expressed, NVL is found at highest levels in pancreas, retina, heart, skeletal muscle and placenta.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NVL polyclonal Antibody detects endogenous levels of NVL protein.
Molecular Weight: ~ 95 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Nuclear valosin-containing protein-like; NVLp; Nuclear VCP-like protein
Immunogen: Synthetic peptide, corresponding to amino acids 393-438 of Human NVL.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: