Product Description
Thrombomodulin polyclonal Antibody | BS5650 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Thrombomodulin polyclonal Antibody detects endogenous levels of Thrombomodulin protein.
Molecular Weight: ~ 60, 105 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM
Immunogen: Synthetic peptide, corresponding to amino acids 530-575 of Human Thrombomodulin.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: