Product Description
TUBB2A (Acetyl-K379) polyclonal Antibody | BS64103 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Tubulin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubulin. a and b tubulins form heterodimers which multimerize to form a microtubule filament. Multiple b Tubulin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. g Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both d Tubulin and e Tubulin are associated with the centrosome. d Tubulin is a homolog of the Chlamydomonas d Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. e Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TUBB2A (Acetyl-K379) polyclonal Antibody detects endogenous levels of TUBB2A protein only when acetylated at Lys379. This Antibody also recognizes TUBB2B/3/4A/4B/6 protein when acetylated at the corresponding residues.
Molecular Weight: ~ 49 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Tubulin beta-2A chain; Tubulin beta class IIa; TUBB2A; Tubulin beta-2B chain; TUBB2B; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III; TUBB3; Tubulin beta-4B chain; Tubulin beta-2 chain; Tubulin beta-2C chain; TUBB4B; Tubulin beta chain; Tubulin beta-5 chain; TUBB; Tubulin beta-6 chain; Tubulin beta class V; TUBB6
Immunogen: Synthetic Acetylated peptide derived from human TUBB2A around the Acetylation site of K379.
Conjugate: Unconjugated
Modification: Acetylated
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Histone Lysine Methylation Pathway,Examples of Crosstalk Between Post-translational Modifications,DNA Methylation,