Product Description
UGT8 polyclonal Antibody | BS60393 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: UGT8 polyclonal Antibody detects endogenous levels of UGT8 protein.
Molecular Weight: ~ 61 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; Ceramide UDP-galactosyltransferase; Cerebroside synthase; UDP-galactose-ceramide galactosyltransferase; CGT; UGT4
Immunogen: A synthetic peptide corresponding to residues in Human UGT8.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: