Product Description
ATP6V1B2 polyclonal Antibody | BS70561 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ATP6V1B2 polyclonal Antibody detects endogenous levels of ATP6V1B2 protein.
Molecular Weight: ~ 57 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: HO57; VATB; VPP3; Vma2; ATP6B2; ATP6B1B2;
Immunogen: Recombinant protein of human ATP6V1B2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: