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Product Description
HINT1 polyclonal Antibody | BS72299 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: Hint1, or histidine triad nucleotide-binding protein 1, belongs to the first branch of the HIT superfamily. It hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2. Hint1 also inhibits the activity of the transcription factors AP1, MITF and USF2, as well as influences the transcription process of the Wnt/beta-catenin pathway. In addition, mammalian Hint1 has been suggested to have some tumor suppressor activity.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: HINT1 polyclonal Antibody detects endogenous levels of HINT1 protein.
Molecular Weight: 14kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Histidine triad nucleotide-binding protein 1; Adenosine 5'-monophosphoramidase; Protein kinase C inhibitor 1; Protein kinase C-interacting protein 1; PKCI-1; HINT1; HINT; PKCI1; PRKCNH1
Immunogen: Recombinant protein of human HINT1
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Histone Lysine Methylation Pathway,Examples of Crosstalk Between Post-translational Modifications,DNA Methylation,
