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Product Description
IRF-4 polyclonal Antibody | BS6104 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IF
Application Range: WB: 1:500~1:2000 IF: 1:50~1:200
Background: Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IRF4 polyclonal Antibody detects endogenous levels of IRF4 protein.
Molecular Weight: ~ 52 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Interferon regulatory factor 4; Lymphocyte-specific interferon regulatory factor; LSIRF; Multiple myeloma oncogene 1; NF-EM5; IRF4; MUM1
Immunogen: Recombinant full length Human IRF-4.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
