Product Description
NR2E1 polyclonal Antibody | BS8915 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IF IP
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:100 IP 1:50 - 1:100
Background: NR2 proteins are a large family of nuclear hormone receptor transcription factors. The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding. NR2E1 (nuclear receptor subfamily 2, group E, member 1), also known as TLX, is an essential component in the formation of synaptic plasticity and dendritic structure in retinal astrocytes. In addition, NR2E1 is a orphan receptor that binds DNA as part of the hormone response element (HRE), a transcription regulator for hormones. DNA-binding orphan receptors have the conserved sequence 5'-AAGGTCA-3', a motif that determines substrate binding specificity. NR2E1 is expressed in brain tissue, with highest levels in astrocytes, and is localized to the nucleus.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NR2E1 polyclonal Antibody detects endogenous levels of NR2E1 protein.
Molecular Weight: ~ 43kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Nuclear receptor subfamily 2 group E member 1; Nuclear receptor TLX; Protein tailless homolog; Tll; hTll; NR2E1; TLX
Immunogen: Recombinant full length Human NR2E1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Vesicle Trafficking presynaptic signaling,