Product Description
ATF6 polyclonal Antibody | BS6476 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background: ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ATF6 polyclonal Antibody detects endogenous levels of ATF6 protein.
Molecular Weight: ~74 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Activating transcription factor 6 alpha; Activating transcription factor 6; ATF 6; ATF6 alpha; ATF6; ATF6-alpha; ATF6A; ATF6A; cAMP dependent transcription factor ATF 6 alpha; cAMP-dependent transcription factor ATF-6 alpha; Cyclic AMP dependent transcription factor ATF 6 alpha; DKFZp686P2194; ESTM49; FLJ21663; Processed cyclic AMP dependent transcription factor ATF 6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 alpha;
Immunogen: Recombinant full length Human ATF6.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Regulation of Apoptosis,Inhibition of Apoptosis,B cell receptor signaling,Mitochondrial Control of Apoptosis,