Product Description
BAF53 polyclonal Antibody | BS8473 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB,IHC
Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200
Background: The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: BAF53 polyclonal Antibody detects endogenous levels of BAF53 protein.
Molecular Weight: ~ 47kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Actin-like protein 6A; 53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit K; ACTL6A; BAF53; BAF53A; INO80K
Immunogen: Recombinant full length Human BAF53.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: