Product Description
GBRD polyclonal Antibody | BS65284 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IHC-p,IF (paraffin section),ELISA
Application Range: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Background: gamma-aminobutyric acid type A receptor delta subunit (GABRD) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.
Molecular Weight: ~ 51 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: GABRD; Gamma-aminobutyric acid receptor subunit delta; GABA (A) receptor subunit delta
Immunogen: The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Pathway: