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Product Description
Histone H3 (TriMethyl-K64) polyclonal Antibody | BS74034 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat,Other (Wide Range)
Application: WB,IHC,IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Histone H3 (TriMethyl-K64) polyclonal Antibody detects endogenous levels of Histone H3 protein only when Tri-methylated at Lys64.
Molecular Weight: Refer to Figures
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: H3.4;H3/g;H3FT;H3t
Immunogen: A synthetic Peptide of human TriMethyl-Histone H3-K64
Conjugate: Unconjugated
Modification: Methylated
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Examples of Crosstalk Between Post-translational Modifications,
