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Product Description
MYBPC3 polyclonal Antibody | BS71538 | Bioworld
Host: Rabbit
Reactivity: Rat
Application: WB,IHC
Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200
Background: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MYBPC3 polyclonal Antibody detects endogenous levels of MYBPC3 protein.
Molecular Weight: ~ 170 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FHC; CMH4; CMD1MM; LVNC10; MYBP-C
Immunogen: Recombinant protein of human MYBPC3
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway:
