Product Description
PLSCR3 polyclonal Antibody | BS71668 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse
Application: WB,IHC,IF
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: PLSCR3 polyclonal Antibody detects endogenous levels of PLSCR3 protein.
Molecular Weight: ~ 32 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Phospholipid scramblase 3; PL scramblase 3
Immunogen: Recombinant protein of human PLSCR3
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: