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Product Description
Anti-Mouse CD183/CXCR3 Monoclonal Antibody (Biotin Conjugated) | DL21392F | DLdevelop
Host: Armenian Hamster
Synonyms: C-X-C chemokine receptor type 3, Cxcr3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183/CXCR3
Reactivity: Mouse
Application: FCM
Background: CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4) . CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Concentration: 0.5 mg/mL
Conjugation: Biotin
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: CXCR3-173
Isotype: Armenian Hamster IgG
