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Product Description
Anti-Mouse CD90.2 Monoclonal Antibody (AF647 Conjugated) | DL21092F | DLdevelop
Host: Rat
Synonyms: Thy-1.2 membrane glycoprotein, Thy1.2, Thy-1.2 antigen, CD90.2, Thy-1.2
Reactivity: Mouse
Application: FCM
Background: CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-) . CD90.2 is a glycosylphosphatidylinositol (GPI) -anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Concentration: N/A
Conjugation: AF647
Buffer: PBS with 0.05% Proclin300, 1% BSA
Clone: 30H12
Isotype: Rat IgG2b, κ
