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Product Description
Purified Anti-Mouse/Human CD11b Monoclonal Antibody | DL20934F | DLdevelop
Host: Rat
Synonyms: Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b
Reactivity: Human, Mouse
Application: FCM, IHC, IP
Background: CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Concentration: 0.2 mg/mL
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Clone: M1/70
Isotype: Rat IgG2b, κ
