Product Description
MYBPC3 Polyclonal Antibody | E-AB-63687 | Elabscience
Type: Polyclonal Antibody
Synonyms: MYBPC3, CMD1MM, CMH4, FHC, LVNC10, MYBP-C, cardiac
Application: IHC
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cardiovascular
Background: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human MYBPC3 (NP_000247.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A