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Product Description
IkB alpha Polyclonal Antibody | E-AB-40093 | Elabscience
Type: Polyclonal Antibody
Synonyms: I kappa B alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBA, IKBalpha, MAD 3, MAD3, NF kappa B inhibitor alpha, NFKBI, IKB alpha
Application: IHC
Reactivity: Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signaling transduction
Background: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant human NF-kappa-B inhibitor alpha protein
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: IHC 1:50-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A
![[KO Validated] IKB alpha Polyclonal Antibody](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/295431/455568/sab-signalway-antibody__92073.1641690747__31581.1641691399.gif?c=2 "[KO Validated] IKB alpha Polyclonal Antibody")
