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Product Description
ARHGEF7 Polyclonal Antibody | E-AB-14609 | Elabscience
Type: Polyclonal Antibody
Synonyms: ARHG7, ARHG7, ARHGEF 7, Arhgef7, Beta pix, Beta-Pix, betaPix, betaPix-b, betaPix-c, Cool, COOL-1, COOL1, DKFZp686C12170, DKFZp761K1021, KIAA0142, KIAA0412, mKIAA0142, Nbla10314, P50, P50BP, p85, P85COOL1, P85SPR, PAK interacting exchange factor beta, PAK-interacting exchange factor beta, PAK3, Pak3bp, PIX, PIXB, Rho guanine nucleotide exchange factor (GEF) 7, Rho guanine nucleotide exchange factor (GEF) 7b, Rho guanine nucleotide exchange factor (GEF7), Rho guanine nucleotide exchange factor 7, SH3 domain containing proline rich protein
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction
Background: Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Concentration: 0.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human ARHGEF7
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 90 kDa
Molecular Weight(Observed): N/A
