Product Description
CAST Polyclonal Antibody | E-AB-11022 | Elabscience
Type: Polyclonal Antibody
Synonyms: BS 17, Calpain inhibitor, Calpastatin, Cast, Heart type calpastatin, ICAL, MGC9402, Sperm BS 17 component, Sperm BS-17 component
Application: WB, IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Neuroscience
Background: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
Concentration: 0.8 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human CAST
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 77 kDa
Molecular Weight(Observed): N/A