Product Description
BPGM Polyclonal Antibody | E-AB-18543 | Elabscience
Type: Polyclonal Antibody
Synonyms: 2, 2, 3-bisphosphoglycerate mutase, 2, 3-bisphosphoglycerate mutase, erythrocyte, 2, 3-bisphosphoglycerate synthase, 2, 3-diphosphoglycerate mutase, 3-bisphosphoglycerate mutase, 3-bisphosphoglycerate synthase, 3-diphosphoglycerate mutase, Ab2 098, AI323730, AL022789, Bisphosphoglycerate mutase, BPG dependent PGAM, BPG-dependent PGAM, Bpgm, C86192, DPGM, Erythrocyte 2, 3 bisphosphoglycerate mutase, erythrocyte, PMGE
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Metabolism, Signal transduction
Background: 2, 3-diphosphoglycerate (2, 3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2, 3-DPG synthesis via its synthetase activity, and 2, 3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Concentration: 1.1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Full length fusion protein
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 30 kDa
Molecular Weight(Observed): Refer to figures