Product Description
Caldesmon Polyclonal Antibody | E-AB-13956 | Elabscience
Type: Polyclonal Antibody
Synonyms: CAD, CALD 1, CALD1, CALD1, Caldesmon 1, Caldesmon 1 Isoform 1, Caldesmon 1 Isoform 2, Caldesmon 1 Isoform 3, Caldesmon 1 Isoform 4, Caldesmon 1 Isoform 5, Caldesmon, Caldesmon1, CDM, H CAD, HCAD, L CAD, LCAD, MGC21352, NAG22
Application: WB, IHC, ELISA
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Signal Transduction
Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human Caldesmo
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:150
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 63 kDa
Molecular Weight(Observed): N/A