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Product Description
Mineralocorticoid receptor Polyclonal Antibody | E-AB-70260 | Elabscience
Type: Polyclonal Antibody
Synonyms: Aldosterone receptor, MCR, MGC133092, Mineralocorticoid receptor, MLR, MR, NR3 C2, NR3C2, NR3C2 protein, Nuclear receptor subfamily 3 group C member 2
Application: WB
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Signal Transduction, Cardiovascular, Epigenetics and Nuclear Signaling
Background: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
Concentration: 1.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 107 kDa
Molecular Weight(Observed): 107 kDa
