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Product Description
AF647 Anti-Human CD20 Antibody[2H7] | E-AB-F1212M | Elabscience
Category: Flow Cytometry Antibody
Synonyms: Bp35,Leukocyte surface antigen Leu-16,MS4A1,B-lymphocyte surface antigen B1
Swissprot Code: P11836
Application: FCM
Reactivity: Human
Host: Mouse
Isotype: Mouse IgG2b, κ
Reaserch Area: Cancer, Immunology, Stem cells
Background: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
Concentration: N/A
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Purification Method: N/A
Dilution: N/A
Clone: 2H7
Conjugation: AF647
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