Product Description
FITC Anti-Human CD45RO Antibody[UCHL1] | E-AB-F1139C | Elabscience
Category: Flowcytometry Antibody
Synonyms: N/A
Swissprot Code: P08575
Application: FCM
Reactivity: Human
Host: Mouse
Isotype: Mouse IgG1, κ
Research Areas: Cancer, Cardiovascular, Immunology, Neuroscience, Signal transduction, Stem cells
Backgroun: CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
Concentration: N/A
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Buffer: PBS with 0.05% Proclin300, 1% BSA
Purification Method: N/A
Dilution: N/A
Clone: UCHL1
Conjugation: FITC
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A