Product Description
PerCP/Cyanine5.5 Anti-Human CD279/PD-1 Antibody[J116] | E-AB-F1129J | Elabscience
Category: Flow Cytometry Antibody
Synonyms: PD-1, Programmed Death-1
Swissprot Code: Q15116
Application: FCM
Reactivity: Human
Host: Mouse
Isotype: Mouse IgG1, κ
Reaserch Area: N/A
Background: Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Concentration: N/A
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Purification Method: N/A
Dilution: N/A
Clone: J116
Conjugation: PerCP/Cyanine5.5