Product Description
CERK Polyclonal Antibody | E-AB-10955 | Elabscience
Type: Polyclonal Antibody
Synonyms: Acylsphingosine kinase, Ceramide kinase, Cerk, CERK1, dA59H18.2, dA59H18.3, hCERK, KIAA1646, Lipid kinase 4, Lipid kinase LK4, LK4
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology
Background: CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human CERK
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:25-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A