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Product Description
NECTIN4 Polyclonal Antibody | E-AB-11438 | Elabscience
Type: Polyclonal Antibody
Synonyms: DKFZp686K05193, EDSS1, Ig superfamily receptor LNIR, Nectin 4, Nectin-4, poliovirus receptor-related 4, Processed poliovirus receptor-related protein 4, PRR4, pvrl4, PVRL4
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology
Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Concentration: 0.9 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human PVRL4
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 55 kDa
Molecular Weight(Observed): N/A
