Product Description
SERPINB6 Polyclonal Antibody | E-AB-62871 | Elabscience
Type: Polyclonal Antibody
Synonyms: SERPINB6, CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3, serpin B6
Application: WB
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology
Background: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human SERPINB6 (NP_004559.4).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 42 kDa
Molecular Weight(Observed): 43 kDa