Product Description
CEM/C1 Cell Line | EP-CL-0328 | Elabscience
Background: This cell line exhibits cross resistance to both the water soluble(topotecan) and water insoluble(9-amino-CPT and 10,11-methylenedioxy-CPT) analogs of CPT.CEM/C1 cells are approximately 31 fold less sensitive to CPT than the parental CEM cells.CEM/C1 cells display atypical multidrug resistance(MDR) and altered topoisomerase I catalytic activity.Resistance to CPT is stable for up to six months.
Species: Homo sapiens, Human
Age: 4 years
Tissue: Peripheral blood
Morphology: Lymphoblast
Growth Properties: Suspension
Organism: Homo sapiens, Human
Species Cell: Human
application: N/A
Doubling Time: N/A
Biosafety: 1
Subculturing: Cultures can be maintained by the addition of fresh medium or replacement of medium. Alternatively, cultures can be established by centrifugation with subsequent resuspension at the subcultivation ratio of 1:2-1:4.
Ratio: 1:2-1:4
Renewal: Every 2 to 3 days