Product Description
DDX3Y Polyclonal Antibody | E-AB-63587 | Elabscience
Type: Polyclonal Antibody
Synonyms: DDX3Y, DBY
Application: IHC, IF
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Developmental Biology, Stem Cells
Background: The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human DDX3Y (NP_001116137.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: IHC 1:50-1:100 IF 1:50-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A