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Product Description
AMPK gamma1 Polyclonal Antibody | E-AB-14562 | Elabscience
Type: Polyclonal Antibody
Synonyms: 5' AMP activated protein kinase gamma 1 subunit, 5' AMP activated protein kinase subunit gamma 1, 5''-AMP-activated protein kinase subunit gamma-1, AAKG1, AMP activated protein kinase noncatalytic gamma 1 subunit, AMPK gamma 1 chain, AMPK gamma1, AMPK subunit gamma-1, AMPKg, MGC8666, PRKAG 1, PRKAG1, Protein kinase AMP activated gamma 1 non catalytic subunit, protein kinase, AMP-activated, noncatalytic gamma-1
Application: WB, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction
Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Concentration: 0.1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human PRKAG1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 38 kDa
Molecular Weight(Observed): N/A
