Product Description
API5 Polyclonal Antibody | E-AB-16168 | Elabscience
Type: Polyclonal Antibody
Synonyms: AAC 11, AAC-11, AAC11, Antiapoptosis clone 11 protein, API 5, API-5, api5, API5 like 1, API5, API5L1, Apoptosis inhibitor 5, Cell migration inducing gene 8 protein, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2 interacting factor 2, Fibroblast growth factor 2-interacting factor, FIF, MIG 8, MIG8, Migration inducing protein MIG8, Protein XAGL
Application: WB, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology
Background: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Concentration: 1.1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human API5
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 59 kDa
Molecular Weight(Observed): N/A