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Product Description
FNIP2 Polyclonal Antibody | E-AB-19877 | Elabscience
Type: Polyclonal Antibody
Synonyms: FNIP1-like protein, Fnip2, FNIP2, FNIPL, Folliculin-interacting protein 2, KIAA1450, MAPO1, O6-methylguanine-induced apoptosis 1 protein, OTTHUMP00000221326
Application: WB, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal transduction
Background: This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin.
Concentration: 1.14 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human FNIP2
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 122 kDa
Molecular Weight(Observed): Refer to figures
