Product Description
MMP7 Polyclonal Antibody | E-AB-10062 | Elabscience
Type: Polyclonal Antibody
Synonyms: Matrilysin, Matrin, Matrix Metalloproteinase 7, Matrix metalloproteinase-7, MMP 7, MMP-7, MMP7, MMP7, MPSL1, PUMP 1, Pump 1 protease, Pump-1 protease, PUMP1, Uterine matrilysin, Uterine metalloproteinase
Application: WB, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human MMP7
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 30 kDa
Molecular Weight(Observed): N/A