Product Description
NAE1 Polyclonal Antibody | E-AB-14592 | Elabscience
Type: Polyclonal Antibody
Synonyms: 59 kDa, A 116A10.1, Amyloid beta precursor protein binding protein 1 59kD, Amyloid beta precursor protein binding protein 1 59kDa, Amyloid beta precursor protein binding protein 1, Amyloid beta precursor protein binding protein 1, 59 kDa, Amyloid beta precursor protein-binding protein 1, Amyloid protein binding protein 1, Amyloid protein-binding protein 1, APP BP1, APP-BP1, APPBP 1, APPBP1, HPP 1, HPP1, NAE 1, NAE1, NEDD8 activating enzyme E1 regulatory subunit, NEDD8 activating enzyme E1 subunit 1, NEDD8 activating enzyme E1 subunit, NEDD8-activating enzyme E1 regulatory subunit, Proto oncogene protein 1, Proto-oncogene protein 1, Protooncogene protein 1, ula 1, ULA1
Application: WB, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology, Epigenetics and Nuclear Signaling
Background: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Concentration: 0.1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human NAE1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 60 kDa
Molecular Weight(Observed): N/A