Product Description
RRAGA Polyclonal Antibody | E-AB-15366 | Elabscience
Type: Polyclonal Antibody
Synonyms: Adenovirus E3 14.7 kDa-interacting protein 1, FIP-1, Rag A, RagA, Ras-related GTP-binding protein A, RRAGA, RRAGA
Application: WB, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Metabolism, Microbiology, Signal Transduction
Background: Ras-related GTP-binding protein Ais aproteinthat in humans is encoded by theRRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human RRAGA
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 37 kDa
Molecular Weight(Observed): N/A