Product Description
RYR1 Polyclonal Antibody | E-AB-13584 | Elabscience
Type: Polyclonal Antibody
Synonyms: CCO, Central core disease of muscle, MHS, MHS1, PPP1R137, Protein phosphatase 1 regulatory subunit 137, Ryanodine receptor 1, RYDR, RYR, RYR-1, RyR1, RYR1, sarcoplasmic reticulum calcium release channel, Skeletal muscle calcium release channel, Skeletal muscle ryanodine receptor, Skeletal muscle-type ryanodine receptor, SKRR, Type 1 ryanodine receptor
Application: WB, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience
Background: This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.
Concentration: 0.5 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human RYR1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 565 kDa
Molecular Weight(Observed): N/A