Product Description
HDAC6 Monoclonal Antibody | PA6120 | Elabscience
Clone: YN00946m
Reactivity: Human
Host: Mouse
Application: Immunohistochemistry-P
Category Type: RTU for IHC
Swissprot: Q9UBN7
Concentration: 100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
Buffer: TBS with 0.1% Proclin300, PH7.4
Background: Histone deacetylase (HDAC) is a kind of protease, which plays an important role in the structural modification of chromosomes and the regulation of gene expression. In general, histone acetylation is conducive to the dissociation of DNA and histone octamer, and the relaxation of nucleosome structure, so that various transcription factors and co transcription factors can specifically bind to DNA binding sites, and activate gene transcription. In the nucleus, histone acetylation and histone deacetylation are in a dynamic equilibrium, and are regulated by histone acetyltransferase (HAT) and histone deacetylase (HDAC).
Location: Cytoplasm