Product Description
PDPK1 Polyclonal Antibody | E-AB-32535 | Elabscience
Type: Polyclonal Antibody
Synonyms: 3 phosphoinositide dependent protein kinase 1, 3-phosphoinositide-dependent protein kinase 1, hPDK 1, hPDK1, MGC20087, MGC35290, OTTHUMP00000159109, OTTHUMP00000159110, OTTHUMP00000174525, PDK1, Pdpk1, PDPK1, PDPK2, PDPK2P, PkB kinase, PkB kinase like gene 1, PkB like 1, PRO0461, Protein kinase
Application: WB, IHC-p, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction
Background: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from human PDK1 around the non-phosphorylation site of Ser241.
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 63 kDa
Molecular Weight(Observed): 60 kDa